Evaluation of four Narcissus Cultivars as Potential Sources for Galanthamine Production

Rita M. Moraes-Cerdeira; Charles L. Burandt; Jairo K. Bastos; N. P. Dhammika Nanayakkara; Julie Mikell; Jeffrey Thurn; James D. McChesney

doi:10.1055/s-2006-957740

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Planta Med 1997; 63(5): 472-474
DOI: 10.1055/s-2006-957740

Letters

Evaluation of four Narcissus Cultivars as Potential Sources for Galanthamine Production

Rita M. Moraes-Cerdeira¹ , Charles L. Burandt¹ Jr , Jairo K. Bastos¹ , N. P. Dhammika Nanayakkara¹ , Julie Mikell¹ ^, ² , Jeffrey Thurn¹ , James D. McChesney¹ ^, ² ^, ³

¹National Center for the Development of Natural Products and The Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA
²Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA
³Present address: NaPro BioTherapeutics, Inc., 6304 Spine Road Unit A, Boulder, Colorado 80301, USA

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Publication History

1996

1997

Publication Date:
04 January 2007 (online)

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Abstract

Galanthamine, an alkaloid present in the Amaryllidaceae is currently undergoing clinical trials for the treatment of Alzheimer's. Common daffodils, Narcissus spp., contain galanthamine and other alkaloids. Four commercial Narcissus cultivars were evaluated as potential sources of galanthamine. Planting depths, planting densities, bulb size or flower bud removal did not affect galanthamine content.