Phytochemical Analysis of Geigeria alata and Francoeuria crispa Essential Oils

Samir A. Ross; Khalid A. El Sayed; Mahmoud A. El Sohly; Mark T. Hamann; Osama B. Abdel-Halim; Atallah F. Ahmed; Mamdouh M. Ahmed

doi:10.1055/s-2006-957743

Planta Med 1997; 63(5): 479-482
DOI: 10.1055/s-2006-957743

Letters

Phytochemical Analysis of Geigeria alata and Francoeuria crispa Essential Oils

Samir A. Ross¹ ^, ² , Khalid A. El Sayed² , Mahmoud A. El Sohly¹ ^, ³ , Mark T. Hamann¹ ^, ² , Osama B. Abdel-Halim⁴ , Atallah F. Ahmed⁴ , Mamdouh M. Ahmed⁴

¹The National Center for The Development of Natural Products and Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38697, U.S.A
²Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, U.S.A.
³Department of Pharmaceutics, School of Pharmacy, The University of Mississippi, University, MS 38677, U.S.A.
⁴Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, Mansoura 35511, Egypt

Abstract

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Abstract

Phytochemical analyses of Geigeria alata (Benth. & Hook.) and Francoeuria crispa (Forssk., Cas.) (Asteraceae) essential oils were performed. G. alata oil showed moderate in vitro cytotoxicity (IC₅₀, µg/ml against tumor cells; P388: 2.0, A-549:2.5 and HT-29: 5.0), and also showed weak anti-HIV activity. S-Carvotanacetone, the major component of F. crispa oil (93.0%), was isolated and its structure was elucidated by 2D-NMR analysis.

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