Studies on the Constituents of Roots of Scutellaria planipes

Abstract

From the roots of Scutellaria planipes (L.), three new flavonoids, 5,7,3′,6′-tetrahydroxy-6,8,2′-trimethoxyflavone (1), (2R,3R)-3,5,7,2′,5′-pentahydroxyflavanone (2) and 7,2′-dihydroxy-5-methoxyflavone (3) were isolated, together with ten known flavonoids, skullcapflavone I (4), wogonin (5), baicalein (6), norwogonin (7), viscidulin III (8), 5,7,2′,6′-tetrahydroxy-flavone (9), 3,5,7,2′,6′-pentahydroxyflavone (10), wogonin 7-O-β-D-glucuronide (11), baicalin (12), baicalein 7-O-β-D-glucopyranoside (13), and three phenethyl alcohol glycosides, acteoside (14), martynoside (15), and jionoside D (16). The structures were elucidated by spectroscopic methods.

Key words

Scutellaria planipes - Labiatae - 5,7,3′,6′-tetrahydroxy-6,8,2′-trimethoxyflavone - (2R,3R)-3,5,7,2′,5′-pentahydroxyflavanone - 7,2′-dihydroxy-5-methoxyflavone