Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000058.xml
Planta Med 1997; 63(6): 552-553
DOI: 10.1055/s-2006-957763
DOI: 10.1055/s-2006-957763
Letters
© Georg Thieme Verlag Stuttgart · New York
Polyacetylene Analogs, Isolated from Hairy Roots of Panax ginseng, Inhibit Acyl-CoA : Cholesterol Acyltransferase
Further Information
Publication History
1997
1997
Publication Date:
04 January 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/199706/lookinside/thumbnails/10.1055-s-2006-957763-1.jpg)
Abstract
In the course of our screening program for acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors from Korean herbal medicines, ACAT inhibitors were isolated from the hairy roots of Panax ginseng (Araliaceae) and identified as panaxynol, panaxydol, panaxydiol, and panaxytriol. These active compounds inhibit rat liver ACAT with IC50 values of 94, 80, 45 and 79 µM, respectively.