Antispasmodic and Spasmogenic Effects of Scolymus hispanicus and Taraxasteryl Acetate on Isolated Ileum Preparation

Neş'e Kirimer; Zeynep Tunalier; K. Hüsnü Can Başer; Ipek Cingi

doi:10.1055/s-2006-957765

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Planta Med 1997; 63(6): 556-558
DOI: 10.1055/s-2006-957765

Letters

Antispasmodic and Spasmogenic Effects of Scolymus hispanicus and Taraxasteryl Acetate on Isolated Ileum Preparation

Neş'e Kirimer¹ , Zeynep Tunalier¹ , K. Hüsnü Can Başer¹ , Ipek Cingi²

¹Anadolu University, Medicinal and Aromatic Plant and Drug Research Centre (TBAM), TR-26470 Eskişehir, Turkey
²Osmangazi University, Faculty of Medicine, Department of Pharmacology, TR-26040 Eskişehir, Turkey

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Publication History

1997

1997

Publication Date:
04 January 2007 (online)

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Abstract

Taraxasteryl acetate (1) was identified as the major triterpenoid of the ethanolic extract of the root bark of Scolymus hispanicus L. Antispasmodic and spasmogenic effects of the ethanolic extract, its fractions, taraxasteryl acetate, and a fluid extract of this plant were tested on isolated rat ileum preparations. The strong biphasic responses observed suggested a possible lithuretic activity of the compounds and the fractions tested.