Secoiridoid Glucosides from Swertia mileensis

Abstract

Five new acyl secoiridoid glucosides along with three known secoiridoid glucosides, swertiamarin, 2′-O-acetylswertiamarin, and amarogentin, were isolated from the aerial parts of Swertia mileensis. The structures of these compounds were determined to be 2′-O-acetyl-4′-O-trans-feruloylswertiamarin, 2′-O-acetyl-4′-O-cis-feruloylswertiamarin, 2′-O-acetyl-4′-O-trans-p-coumaroylswertiamarin, 2′-O-acetyl-4′ -O-cis-p-coumaroylswertiamarin, and 4′-O-trans-p-coumaroylswertiamarin from spectroscopic evidence.

Key words

Swertia mileensis - Gentianaceae - acylated secoiridoid glucosides - swertiamarin