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DOI: 10.1055/s-2006-957793
© Georg Thieme Verlag Stuttgart · New York
11α,13- and 11β,13 -Dihydro-4H-xanthalongin 4-O-β-Glucopyranosides: New Sesquiterpene Lactone Glycosides from Flowers of Arnica amplexicaulis and A. mollis 1,*
1 Presented in parts as poster at the Jahrestagung der Deutschen Pharmazeutischen Gesellschaft, Berlin, 1990 (1)* Dedicated to Prof. Dr. H. Rimpler, Freiburg, on the occasion of his 60th birthday.Publication History
1995
1995
Publication Date:
04 January 2007 (online)
Abstract
The flowers of A. amplexicaulis afforded, in addition to xanthalongin (1), 11β,13-dihydroxanthalongin (2), its 11-epimer (3), and 11α,13-dihydro-4H-xanthalongin (4), the new xanthanolide glycosides 11α, 13-dihydro-4H-xanthalongin 4-O-β-D-glucopyranoside (5) and its 11-epimer (6). The glycosides were also isolated from the flowers of A. mollis. The structures were elucidated by NMR spectroscopy 1H-NMR, COSY, 13C-NMR, HETCOR, DEPT), MS (EI, FAB, FD), and enzymatic hydrolysis of the glycosides. The chemo-taxonomic importance is discussed.
Key words
Arnica amplexicaulis - A. mollis - Asteraceae - sesquiterpene lactones - xanthanolides and xanthanolide glucosides - chemotaxonomy