Abstract
The influence of three compounds of the essential oil of Chamomilla recutita (L.) Rauschert on the protamine sulphate-provoked degranulation of mast cells from Lewis-1a rats was investigated. The effect was determined by measuring histamine liberation fluorometrically. Chamazulene and (-)-α-bisabolol had no distinct effects. The en-yne dicycloether partly inhibited the degranulation in concentrations above 10-4 M.