A DNA-Damaging Sesquiterpene and Other Constituents from Frullania nisquallensis

Youn C. Kim; Vanderlan da S Bolzani; Nina Baj; A. A. Leslie Gunatilaka; David G. I. Kingston

doi:10.1055/s-2006-957800

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Planta Med 1996; 62(1): 61-63
DOI: 10.1055/s-2006-957800

Letter

A DNA-Damaging Sesquiterpene and Other Constituents from Frullania nisquallensis

Youn C. Kim¹ , Vanderlan da S. Bolzani² , Nina Baj¹ , A. A. Leslie Gunatilaka¹ , David. G. I. Kingston¹

¹Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0212, U.S.A.
²Instituto de Quimica, Universidade Estadual Paulista, CP.355, 14.800, Araraquara, SP, Brazil

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Publication History

1995

1995

Publication Date:
04 January 2007 (online)

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Abstract

Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). ¹³C-NMR data of 3 are reported.