Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000058.xml
Planta Med 1996; 62(2): 175-176
DOI: 10.1055/s-2006-957846
DOI: 10.1055/s-2006-957846
Letters
© Georg Thieme Verlag Stuttgart · New York
Indolopyridoquinazoline Alkaloids with Antiplatelet Aggregation Activity from Zanthoxylum integrifoliolum
Further Information
Publication History
1995
1995
Publication Date:
04 January 2007 (online)

Abstract
Bioassay-guided fractionation led to the isolation of three indolopyridoquinazoline alkaloids, 1-hydroxyrutaecarpine, rutaecarpine, and 1-methoxyrutaecarpine as the active principles of antiplatelet aggregation in vitro, from the chloroform-soluble part of the fruit of Zanthoxylum integrifoliolum (Rutaceae). 1-Hydroxyrutaecarpine exhibited antiplatelet activity induced by AA and showed an IC50 value of ca. 1-2 µg/ml.