2′-Hydroxycinnamaldehyde from Stem Bark of Cinnamomum cassia

Byoung-Mog Kwon; Young-Kwon Cho; Seung-Ho Lee; Ji-Youn Nam; Song-Hae Bok; Soo-Kyoung Chen; Jeong-Ah Kim; Ihn-Rhan Lee

doi:10.1055/s-2006-957851

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Planta Med 1996; 62(2): 183-184
DOI: 10.1055/s-2006-957851

Letters

2′-Hydroxycinnamaldehyde from Stem Bark of Cinnamomum cassia

Byoung-Mog Kwon¹ , Young-Kwon Cho¹ , Seung-Ho Lee¹ , Ji-Youn Nam¹ , Song-Hae Bok¹ , Soo-Kyoung Chen² , Jeong-Ah Kim² , Ihn-Rhan Lee²

¹Bioproducts RG, Korea Research Institute of Bioscience & Biotechnology, KIST, P.O. Box 115 Yoosung, Taejon, Korea 305-600
²Ewha Womans University, College of Pharmacy, Seoul, Korea

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Publication History

1995

1995

Publication Date:
04 January 2007 (online)

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Abstract

2′-Hydroxycinnamaldehyde, which inhibits farnesylprotein transferase (FPTase), has been isolated from the stem bark of Cinnamomum cassia Blume. The biologically active agent in the extract has been purified by silica column chromatography and HPLC. The structure of the isolated compound was elucidated on the basis of 500 MHz NMR experiments.