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Planta Med 1996; 62(3): 283-285
DOI: 10.1055/s-2006-957882
Letter

© Georg Thieme Verlag Stuttgart · New York

Picroliv Protects Against Alcohol-Induced Chronic Hepatotoxicity in Rats1

Ravi Rastogi2 , Seema Saksena2 , Narendra Kumar Garg2 , Narinder Kumar Kapoor2 , Dharam Pal Agarwal3 , Bhola Nath Dhawan4
  • 2Biochemistry Division, C. D. R. I., Lucknow
  • 3Institute of Human Genetics, University of Hamburg, Hamburg, Germany
  • 4ICMR Centre for Advanced Research in Traditional Remedies, Central Drug Research Institute, Lucknow 226 001, India
1 C.D.R.I. Communication No. 5346
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1995

1995

Publication Date:
04 January 2007 (online)

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Abstract

Daily administration of ethyl alcohol (3.76 g/kg, p.o.) for 45 days resulted in significant changes in several biochemical parameters of the liver and serum of albino rats. After exposure to alcohol for 30 days when Picroliv (12 mg/kg, p.o.), an iridoid glycoside fraction of Picrorhiza kurroa, was administered for 15 days along with alcohol, the degree of change in most of the parameters was reduced.