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Planta Med 1996; 62(4): 353-354
DOI: 10.1055/s-2006-957901
Letters

© Georg Thieme Verlag Stuttgart · New York

The Cytotoxicity of Psoralidin from Psoralea corylifolia

Yong-Man Yang1 , Jin-Won Hyun1 , Min-Sook Sung1 , Ha-Sook Chung3 , Byong-Kak Kim1 , Woo-Hyun Paik2 , Sam-Sik Kang3 , Jae-Gahb Park1
  • 1Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine, Seoul 110-744, Korea
  • 2Central Research Institute, Boryung Pharmaceutical Co., Ltd., Kunpo-Si 435-050, Korea
  • 3Natural Products Research Institute, Seoul National University, Seoul 110-460, Korea
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Publikationsverlauf

1995

1996

Publikationsdatum:
04. Januar 2007 (online)

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Abstract

A cytotoxic coumestan derivative, psoralidin (1), was isolated from the seed of Psoralea corylifolia. The IC50 values of 1 against SNU-1 and SNU-16 carcinoma cell lines were 53 and 203 µg/ml, respectively, indicating cytotoxic activity against stomach carcinoma cell lines.