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Planta Med 1996; 62(5): 458-461
DOI: 10.1055/s-2006-957939
Paper

© Georg Thieme Verlag Stuttgart · New York

Alkaloids from Aspidosperma Species from Bolivia

A.-C. Mitaine1 , K. Mesbah1 , B. Richard1 , C. Petermann1 , S. Arrazola2 , C. Moretti3 , M. Zèches-Hanrot1 , L. Le Men-Olivier1
  • 1Faculté de Pharmacie (U.R.A. au C.N.R. S. n° 492), 51, rue Cognacq-Jay, F-51096 Reims Cedex, France
  • 2C.I.B.E. Universidad Mayor de San Simon, C. P. 992 Cochabamba, Bolivia
  • 3ORSTOM (UR n° 45), 213 me Lafayette, F-75480 Paris Cedex 10, France
Further Information

Publication History

1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

Two Bolivian Aspidosperma species were investigated. The seed and stem bark of Aspidosperma macrocarpon Mart. contain six known alkaloids: (-)-vincadifformine, ervinceine, kopsanone, kopsinine, kopsanol in the seed, and kopsanone, kop-sinine, kopsanol, 18-epikopsanol in the stem bark. The stem bark of Aspidosperma pyrifolium Mart. contains eleven known alkaloids: (-)-vincadifformine, O-demethylpalosine, haplocine, N-formylaspidospermidine, vallesine, demethoxyaspidospermine, palosine, (-)-aspidospermine, aspidospermidine, akuammicine, tubotaiwine, beside the two new bases dehydroxyhaplocidine and 10-methoxyaspidospermidine.

Key words

Aspidosperma macrocarpon - A. pyrifolium - Apocynaceae - indole alkaloids