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Planta Med 1995; 61(2): 146-149
DOI: 10.1055/s-2006-958035
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© Georg Thieme Verlag Stuttgart · New York

Bioactive Constitutents from the Stems of Annona montana

Yang-Chang Wu1 , Gwo-Yuan Chang1 , Feng-Nien Ko2 , Che-Ming Teng2
  • 1Graduate Institute of Natural Products, Koahsiung Medical College, Kaohsiung 807, Taiwan, Republic of China
  • 2Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
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Publication History

1994

1994

Publication Date:
04 January 2007 (online)

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Abstract

Three structurally related acid amides, N-trans-feruloyltyramine (1), N-p-coumaroyltyramine (2), and N-trans-caffeoyltyramine (3), one lignan, (-)-syringaresinol (4), one aromatic aldehyde, syringaldehyde (5), and two steroids, β-sitosterol and β-sitosterol-β-D-glucoside were isolated from the stem parts of Annona montana (Annonaceae). N-trans-Caffeoyltyramine (3) is a new natural compound. These compounds and their acetate derivatives were subjected to the antiplatelet aggregation and cytotoxicity bioassay where some of them showed significant activities.

Key words

N-trans-Caffeoyltyramine - Annonaceae - Annona montana - cytotoxicity - antiplatelet aggregation