The Effect of Chelidonium majus Herb Extract on Choleresis in the Isolated Perfused Rat Liver

U. Vahlensieck; R. Hahn; H. Winterhoff; H. G. Gumbinger; A. Nahrstedt; F. H. Kemper

doi:10.1055/s-2006-958070

Planta Medica, Table of Contents

Planta Med 1995; 61(3): 267-270
DOI: 10.1055/s-2006-958070

Letter

The Effect of Chelidonium majus Herb Extract on Choleresis in the Isolated Perfused Rat Liver

U. Vahlensieck¹ , R. Hahn² , H. Winterhoff¹ , H. G. Gumbinger¹ , A. Nahrstedt² , F. H. Kemper¹

¹Institut für Pharmakologie und Toxikologie der Westfälischen-Wilhelms Universität, Domagkstr.12, D-48149 Münster, Germany
²Institut für Pharmazeutische Biologie und Phytochemie der Westfülischen-Wilhelms Universitüt, Hittorfstr. 56, D-48149 Münster, Germany

Abstract

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Abstract

The total ethanolic extract, the phenolic and the alkaloidal fraction of the herb of Chelidonium majus L. (Papaveraceae) were tested for their choleretic activity using the isolated perfused rat liver. The total extract significantly caused chloresis by increasing the bile acid independent flow (BAIF); the observed weak activity of both fractions, tested each and as combination, however, was not significant.

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