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Planta Med 1995; 61(4): 368-369
DOI: 10.1055/s-2006-958105
Letters

© Georg Thieme Verlag Stuttgart · New York

Cytotoxicity of Diterpenes from Premna schimperi and Premna oligotricha

Solomon Habtemariam
  • Department of Physiology and Pharmacology, University of Strathclyde, Glasgow, Gl 1XW, U.K.
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Publication History

1994

1995

Publication Date:
04 January 2007 (online)

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Abstract

The cytotoxicity of two diterpenes from Premna schimperi and Premna oligotricha (Verbenaceae) was studied using the MTT assay. Their cytotoxic activity against three human (HeLa, SK.N.SH, and ECV 304) and two murine (L929 and RAW 264.7) carcinoma cell lines varied between 1.5 to 35 µg/ml and was comparable with azauridine and chlorambucil.