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Planta Med 1995; 61(5): 472-474
DOI: 10.1055/s-2006-958140
Letter

© Georg Thieme Verlag Stuttgart · New York

Effects of Catechins on the Mouse Tumor Cell Adhesion to Fibronectin

Kuninori Ogata1 , Noriyuki Mukae1 , Yasuo Suzuki1 , Ken Satoh2 , Koh Narumi2 , Toshihiro Nukiwa2 , Mamoru Isemura1
  • 1Laboratory of Biochemistry, School of Food and Nutritional Sciences, The University of Shizuoka, Yada, Shizuoka 422, Japan
  • 2Department of Respiratory Medicine, Institute of Development, Aging and Cancer, Tohoku University, Sendai 980, Japan
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1994

1995

Publikationsdatum:
04. Januar 2007 (online)

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Abstract

We studied the effects of 5 kinds of catechins on the adhesion of mouse lung carcinoma 3LL and melanoma B16F10 cells to the fibronectin substratum. (-)-Epicatechin gallate and (-)-epigallocatechin gallate were active in inhibiting the 3LL cell adhesion, while (+)-catechin, (-)-epicatechin, and (-)-epi-gallocatechin were inactive. Gallate-containing catechins also impaired adhesion and/or spreading of B16F10 cells.