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Planta Med 1995; 61(5): 475-477
DOI: 10.1055/s-2006-958141
Letter

© Georg Thieme Verlag Stuttgart · New York

Screening for in vitro Antifungal Activities of some Indole Alkaloids

J. Quetin-Leclercq1 , A. Favel2 , G. Balansard3 , P. Regli2 , L. Angenot1
  • 1Laboratoire de Pharmacognosie, Institut de Pharmacie, rue Fusch, 5, B-4000 Liège, Belgium
  • 2Laboratoire de Botanique et de Cryptogamie, Faculté; de Pharmacie, bld J. Moulin, 27, F-13385 Marseille Cedex 5, France
  • 3Laboratoire de Pharmacognosie, Faculté de Pharmacie, bid J. Moulin, 27, F-13385 Marseille Cedex 5, France
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Publication History

1994

1995

Publication Date:
04 January 2007 (online)

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Abstract

Several indole alkaloids were tested by the agar dilution technique on a panel of human pathogenic fungi, yeasts, and dermatophytes. Our results indicate that the most active compounds possess a β-carboline skeleton and that the presence of a 3-4 double bond enhances the activity. Our results also show that antifungal activities are not linked to the cytotoxic, antimicrobial or antiparasitic properties.