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Planta Med 1995; 61(5): 482-484
DOI: 10.1055/s-2006-958145
Letter

© Georg Thieme Verlag Stuttgart · New York

Two New 6-Alkylcoumarins from Angelica pubescens f. biserrata

Jiang-hua Liu1 , Sui-xu Xu2 , Xin-sheng Yao3 , Hisayoshi Kobayashi3
  • 1Department of Phytochemistry, Liaoning College of Traditional Chinese Medicine, Shenyang 110032, People's Republic of China
  • 2Department of Phytochemistry, Shenyang Pharmaceutical University, Shenyang, People's Republic of China
  • 3Institute of Applied Microbiology, Tokyo University, Tokyo, Japan
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1994

1995

Publication Date:
04 January 2007 (online)

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Abstract

Two new 6-alkylcoumarins, angelitriol (1) and angelol J (2), were isolated from the EtOAc-soluble fraction of the roots of Angelica pubescens Maxim f. biserrata Shan et Yuan. Their structures were elucidated as 6-[(1R,2S)-1,2,3-trihydroxy-3-methylbutyl]-7-methoxycoumarin (1) and 6-[(1R,2R)-1-ethoxy-2,3-dihydroxy-3-methylbutyl]-7-methoxycoumarin (2), respectively, on the basis of spectral evidence. Both of them showed strong inhibitory effects on human platelet aggregation.