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Synthesis 2007(3): 351-354  
DOI: 10.1055/s-2006-958962
PAPER
© Georg Thieme Verlag Stuttgart · New York

4,4,6-Trimethyl-1,3,2-dioxaborinane: A Practical Reagent for Palladium-Catalyzed­ Borylation of Aryl Halides

Miki Murata*, Takeshi Oda, Shinji Watanabe, Yuzuru Masuda
Department of Materials Science, Kitami Institute of Technology, Kitami 090-8507, Japan
Fax: +81(157)264973; e-Mail: muratamk@mail.kitami-it.ac.jp;
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Publication History

Received 20 September 2006
Publication Date:
21 December 2006 (online)

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Abstract

The palladium-catalyzed borylation of aryl iodides with 4,4,6-trimethyl-1,3,2-dioxaborinane is described. The mild reaction conditions employed allow for aryl iodides with a wide variety of functional groups to be tolerated. The products of this borylation were coupled with aryl halides to give biaryls in good yields.

Key words

boron - palladium - catalysis - cross-coupling - aryl halides