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Planta Med 1995; 61(6): 562-563
DOI: 10.1055/s-2006-959374
Letters

© Georg Thieme Verlag Stuttgart · New York

Larvicidal Constituents of Melantheria albinervia

R. Slimestad1 , A. Marston1 , S. Mavi2 , K. Hostettmann1
  • 1Institut de Pharmacognosie et Phytochimie, Université de Lausanne, B.E.P., CH-1015 Lausanne, Switzerland
  • 2National Herbarium and National Botanic Garden, Causeway, Harare, Zimbabwe
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Publication History

1995

1995

Publication Date:
04 January 2007 (online)

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Abstract

Bioactivity-guided fractionation has led to the isolation of two larvicidal diterpenes, active against the yellow fever-transmitting mosquito Aedes aegypti, from a dichloromethane root extract of Melantheria albinervia (Asteraceae), a plant from Zimbabwe. These diterpenes were identified as ent-kaur-16-en-19-oic acid and 9(ll),16-kauradien-19-oic acid. The diterpenes were also weakly active against Bacillus subtilis.