Planta Medica, Inhaltsverzeichnis Planta Med 1994; 60(4): 360-364DOI: 10.1055/s-2006-959501 Papers © Georg Thieme Verlag Stuttgart · New York Caffeoylquinic Acids and Some Biological Activities of Pluchea symphytifolia E. Scholz1 , M. Heinrich1 , D. Hunkler2 1Institut für Pharmazeutische Biologie der Universität, Schänzlestr. 1, D-79104 Freiburg/B., Federal Republic of Germany 2Institut für Organische Chemie und Biochemie der Universität, Albertstr. 21, D-79104 Freiburg/B., Federal Republic of Germany Artikel empfehlen Abstract als PDF herunterladen Artikel einzeln kaufen Abstract From the aerial parts of Pluchea symphytifolia, four known and two new caffeoylquinic acids, 1,3,4,5-tetra-O-caffeoylquinic acid and 1,3-di-O-[3,4-bis-(3,4-dihydroxyphenyl)-cyclobutane-1,2-dicarbonyl]-4,5-di-O-caffeoylquinic acid, and two flavonols were isolated and their structures elucidated by mass and NMR spectroscopy and by chemical degradation. The aqueous extract had weak antibacterial and weak antisecretory effects; the lipophilic extract showed a modest anthelmintic activity. The higher caffeoylated quinic acids participated in the antibacterial and anthelmintic effect of the extracts. Key words Pluchea symphytifolia - Asteraceae - 1,3,4,5-tetra-O-caffeoylquinic acid - photodimer - antimicrobial - anthelmintic - antisecretory - astringency PDF (105 kb)
