Biological Activities of Selected Marine Natural Products

Gabriele M. König; Anthony D. Wright; Otto Sticher; Cindy K. Angerhofer; John M. Pezzuto

doi:10.1055/s-2006-959565

Planta Medica, Table of Contents

Planta Med 1994; 60(6): 532-537
DOI: 10.1055/s-2006-959565

Papers

Biological Activities of Selected Marine Natural Products

Gabriele M. König¹ ^, ³ , Anthony D. Wright¹ , Otto Sticher¹ , Cindy K. Angerhofer² , John M. Pezzuto²

¹Department of Pharmacy, Swiss Federal Institute of Technology (ETH) Zurich, Winterthurerstr. 190, CH-8057 Zürich, Switzerland
²Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois 60612, U.S.A.
³Institute of Pharmaceutical Biology, University of Braunschweig, Mendelssohnstr. 1, D-38106 Braunschweig, Federal Republic of Germany

Abstract

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Abstract

Sixty-nine natural products derived from Phaeophyta (brown algae), Rhodophyta (red algae), Porifera (sponges), Cnidaria (soft corals), and Mollusca (nudibranchs) were investigated for their cytotoxic, antimalarial, and antimicrobial effects. Fifty-six were found to mediate a positive response in one or more of these test systems.

Key words

Marine natural products - biological activity

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