The Analgesic Activity of Hedyosmum bonplandianum: Flavonoid Glycosides

Luz Clarena Cárdenas; Jaime Rodríguez; M. Carmen Villaverde; Ricardo Riguera; Rosalina Cadena; Jaime A. Otero

doi:10.1055/s-2006-959597

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Planta Med 1993; 59(1): 26-27
DOI: 10.1055/s-2006-959597

Paper

The Analgesic Activity of Hedyosmum bonplandianum: Flavonoid Glycosides

Luz Clarena Cárdenas¹ , Jaime Rodríguez¹ , M. Carmen Villaverde¹ , Ricardo Riguera¹ , Rosalina Cadena² , Jaime A. Otero²

¹Departamento do Química, Orgánica, Facultad de Química. Universidad de Santiago de Compostela, E-15706-Santiago de Compostela, Spain
²Departamento de Farmacología, Universidad del Valle, A. A. 25360, Cali, Colombia

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Publication History

1991

1992

Publication Date:
04 January 2007 (online)

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Abstract

Kaempferol 3-O-[α-L-rhamnopyranosyl (1→6)-/β-D-glucopyranoside] and kaempferol 3-O-[β-D-glucopyranoside] were isolated from the leaves of Hedyosmum bonplandianum H. B. K. (Chloranthaceae), which is used in Colombian folk medicine as an analgesic. The n-butanol extract and the glycosyl flavonoids isolated exhibited significant analgesic activity in mice.

Key words

Hedyosmum bonplandianum - Chloranthaceae - flavonoid glycosides - kaempferol 3-O-[α-L-rham-nopyranosyl(1→6)-/β-D-glucopyranoside] - kaempferol 3-O-[β-D-glucopyranoside] - Colombian folk medicine - analgesic activity