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Planta Med 1993; 59(2): 135-138
DOI: 10.1055/s-2006-959628
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© Georg Thieme Verlag Stuttgart · New York

Crude Extracts and Two Linear Diterpenes from Cystoseira balearica and their Activity

F. Della Pietá1 , A. R. Bilia2 , M. C. Breschi3 , F. Cinelli1 , I. Morelli2 , R. Scatizzi3
  • 1Dipartimento di Scienze dell' Ambiente e del Territorio, via A. Volta 6, Universita' degli Studi di Pisa, I-56126 Pisa, Italy
  • 2Dipartimento di Chimica Bioorganica, via Bonanno 33, Universita' degli Studi di Pisa, I-56126 Pisa, Italy
  • 3Istituto Policattedra di Discipline Biologiche, via Bonanno 6, Universita' degli Studi di Pisa, I-56126 Pisa, Italy
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Publication History

1992

1992

Publication Date:
04 January 2007 (online)

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Abstract

Crude extracts of Cystoseira balearica were submitted to pharmacological investigations. The chloroform-methanol residue caused relaxation of the rat aortic musculature and an inhibitory action on the guinea pig atria. The fractionation of this crude extract gave two active diterpenoids, eleganolone (1) and elegandiol (2), the latter has not previously been isolated from this alga. These pure components, never before tested, showed a higher activity when compared with the crude residue.

Key words

Cystoseira balearica - brown algae - diterpenoids - antihypertensive activity