Download PDF
Planta Med 1993; 59(4): 323-325
DOI: 10.1055/s-2006-959691
Papers

© Georg Thieme Verlag Stuttgart · New York

Linoleate-Rich Triacylglycerol in Panax pseudo-ginseng Improves Erythrocyte Deformability in vitro

C. Y. Hong1 , 2 , 4 , L. J. Lai4 , S. F. Yeh3
  • 1Institute of Traditional Medicine, National Yang-Ming Medical College, Shih-Pai, Taipei, Taiwan
  • 2Institute of Clinical Medicine, National Yang-Ming Medical College, Shih-Pai, Taipei, Taiwan
  • 3Institute of Biochemistry, National Yang-Ming Medical College, Shih-Pai, Taipei, Taiwan
  • 4Department of Medicine, Veterans General Hospital, Taipei, Taiwan
Further Information

Publication History

1992

1992

Publication Date:
04 January 2007 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

With field's filtration technique as a bio-assay for evaluating red blood cell (RBC) deformability, we purified from Panax pseudo-ginseng an active component that improved the deformability of calcium-loaded RBC. NMR and mass spectrometric studies showed that the purified substance was a triacylglycerol (TG) with linoleic acid as the major fatty acid residue in the esterified positions of glycerol. The mechanism for this TG to improve RBC deformability could be a modification of membrane fluidity rather than a competitive antagonism with calcium ion.

Key words

Panax pseudo-ginseng - erythrocyte deformability - triacylglycerol - calcium ion - linoleic acid