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Planta Med 1993; 59(4): 333-336
DOI: 10.1055/s-2006-959694
DOI: 10.1055/s-2006-959694
Papers
© Georg Thieme Verlag Stuttgart · New York
Antidiarrhoeic Activity of Euphorbia hirta Extract and Isolation of an Active Flavonoid Constituent
Weitere Informationen
Publikationsverlauf
1992
1992
Publikationsdatum:
04. Januar 2007 (online)
Abstract
The antidiarrhoeic activity of the Euphorbia hirta whole plant was investigated. The lyo-philized decoction demonstrated antidiarrhoeic activity in experimental models of diarrhoea induced by castor oil, arachidonic acid, and prostaglandin E2. It showed no activity when magnesium sulphate was used to provoke the diarrhoea. The lyophilized decoction delayed small intestinal transit when this was accelerated by castor oil but not in normal conditions. A flavonoid, quercitrin, with antidiarrhoeic activity was isolated from this crude drug.
Key words
Euphorbia hirta - antidiarrhoeic activity - quercitrin