Abstract
Various fractions of the alcoholic extract of the roots of Salacia macrosperma were evaluated for their antidiabetic activity in alloxan-diabetic rats by estimating
various biochemical parameters in blood, viz. glucose, proteins, lipids, cholesterol,
and free fatty acids, after oral administration for 8 days. From the data obtained,
it is concluded that the methanolic fraction followed by the residual fraction of
the alcoholic extract exhibited significant antidiabetic activity. These biofractions
were able to correct the metabolic abberations in diabetic rats. This activity may
be due to their insulin-like properties.
Key words
Salacia macrosperma
- Hippocrataceae - diabetes mellitus - antidiabetic activity - alloxan-diabetic rats
- insulin-like properties
