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Planta Med 1993; 59(5): 398-400
DOI: 10.1055/s-2006-959717
DOI: 10.1055/s-2006-959717
Paper
© Georg Thieme Verlag Stuttgart · New York
Sedative Effect of Galphimine B, a Nor- seco -triterpenoid from Galphimia glauca
Weitere Informationen
Publikationsverlauf
1992
1993
Publikationsdatum:
04. Januar 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/199305/lookinside/thumbnails/10.1055-s-2006-959717-1.jpg)
Abstract
Galphimia glauca Cav. (Malpighiaceae) is used in Mexican traditional medicine as a sedative in the treatment of mental disorders. Sedative properties of a methanolic extract of the aerial parts of this plant have been established in animal trials and an active compound, named galphimine B, has already been isolated. This compound was submitted to neuropharmacological testing, where it was shown that galphimine B had no significant effect as an anticonvulsant, while it exhibited a strong depressant activity on the nervous system.
Key words
Galphimia glauca - Malpighiaceae - nor-seco-triterpenoid - sedative effects - galphimine B.