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Planta Med 1993; 59(6): 517-520
DOI: 10.1055/s-2006-959751
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© Georg Thieme Verlag Stuttgart · New York

Bioactive Compounds from the Buds of Platanus orientalis and Isolation of a New Kaempferol Glycoside

D. Mitrokotsa1 , S. Mitaku1 , C. Demetzos1 , C. Harvala1 , A. Mentis2 , S. Perez3 , D. Kokkinopoulos3
  • 1Laboratory of Pharmacognosy, Department of Pharmacy, University Campus Zografou, GR-157 71 Athens, Greece
  • 2Department of Bacteriology, Hellenic Pasteur Institute, 127 Vas. Sofias Ave., GR-115 21 Athens, Greece
  • 3Hellenic Anticancer Institute, Department of Immunology, 171 Alexandras Ave., Gr-115 22 Athens, Greece
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Publication History

1993

1993

Publication Date:
04 January 2007 (online)

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Abstract

A new compound kaempferol 3-O-α-L-(2″-E-p-coumaroyl)-rhamnopyranoside, as well as the known flavonoids, kaempferol 3-O-β-D-(6″-E-p-coumaroyl)-glucopyranoside, kaempferol 3-O-α-L-(2″,3″-di-E-p-coumaroyl)-rhamnopyranoside, and caffeic acid were obtained from the methanolic extract of Platanus orientalis L. buds. All the compounds were isolated by column chromatography and identified using 1H-NMR, 2D-1H-NMR (COSY), 1H-13C-NMR, and CIDMS techniques. Cytotoxic and antimicrobial studies were carried out in vitro against human cell lines and against Gram-positive and Gram-negative organisms.

Key words

Plantanus orientalis L - Plantanaceae - kaempferol glycosides - antimicrobial activity - cytotoxicity