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Planta Med 1991; 57(1): 38-40
DOI: 10.1055/s-2006-960012
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© Georg Thieme Verlag Stuttgart · New York

Identification of Some Prostanoids in Aloe vera Extracts

M. Afzal1 , M. Ali1 , R. A. H. Hassan1 , N. Sweedan1 , M. S. I. Dhami2
  • 1Department of Biochemistry, Faculty of Science, University of Kuwait, P. O. Box 5969, Safat-13060, Kuwait
  • 2Department of Biological Sciences, San Jose State University, San Jose, CA 95148, U. S. A.
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Publication History

1989

Publication Date:
05 January 2007 (online)

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Abstract

Screening of extracts from Aloe vera revealed the presence of endogenous arachidonic acid, a potential precursor for the prostanoids synthesis. The presence of endogenous cyclooxygenase, in the plant extracts, was established by radiometric assay. Relatively high proportions of PGE2 and TXB2 and low proportions of other prostaglandins were identified in the plant extract when incubated with [14 C]-arachidonic acid. Other lipids present in this plant were examined and a high percentage of phosphatidylcholine and cholesterol was established. Possible importance of prostaglandins formed endogenously by the plant is discussed.

Key words

Aloe vera - arachindonic acid - prostanoid synthesis