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Planta Med 1991; 57(2): 129-131
DOI: 10.1055/s-2006-960048
DOI: 10.1055/s-2006-960048
Papers
© Georg Thieme Verlag Stuttgart · New York
4-Hydroxy-2-cyclopentenone: An Anti-Pseudomonas and Cytotoxic Component from Passiflora tetrandra 1
1 Antibiotic Compounds from New Zealand Plants; Part IV.Weitere Informationen
Publikationsverlauf
1989
Publikationsdatum:
05. Januar 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/199102/lookinside/thumbnails/10.1055-s-2006-960048-1.jpg)
Abstract
4-Hydroxy-2-cyclopentenone is responsible for the anti-bacterial activity of an extract of leaves from Passiflora tetrandra with minimum inhibitory doses (MID) of ca. 10 µg/disk against Escherichia coli, Bacillus subtilis, and Pseudomonas aeruginosa. 4-Hydroxy-2-cyclopentenone is also cytotoxic to P388 murine leukemia cells (IC50 of < 1 µg/ml).
Key words
Passiflora tetrandra - Passifloraceae - 4-hydroxy-2-cyclopentenone - anti-pseudomonad - cytotoxic