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Planta Med 1991; 57(4): 357-360
DOI: 10.1055/s-2006-960117
DOI: 10.1055/s-2006-960117
Papers
© Georg Thieme Verlag Stuttgart · New York
Isolierung des antiphlogistischen Wirkprinzips von Epilobium angustifolium
Isolation of the Antiphlogistic Active Principle from Epilobium angustifoliumFurther Information
Publication History
1990
Publication Date:
05 January 2007 (online)
Abstract
From the leaves of Epilobium angustifolium L. (Onagraceae) an antiphlogistic principle was isolated and identified as myricetin 3-O-β-D-glucuronide. This novel flavonoid exhibited a very strong anti-inflammatory effect on carrageenan-induced edema in the rat hind paw (more than ten times more effective than indomethacin) and an inhibitory effect on prostaglandin biosynthesis (as effective as indomethacin).
Key words
Epilobium angustifolium - antiphlogistic principle - anti-inflammatory action - inhibition of prostaglandin biosynthesis - myricetin 3-O-β-D-glucuronide