Planta Med 1991; 57(4): 371-375
DOI: 10.1055/s-2006-960120
Papers

© Georg Thieme Verlag Stuttgart · New York

Allicin-Freisetzung aus getrocknetem Knoblauch (Allium sativum): Eine einfach durchzuführende HPTLC-Simultanbestimmung von Allicin und Ajoen in Knoblauchpulver und daraus hergestellten Fertigarzneimitteln

Formation of Allicin from Dried Garlic (Allium sativum): A Simple HPTLC Method for Simultaneous Determination of Allicin and Ajoene in Dried Garlic and Garlic PreparationsGabriele Blania1 , Bernd Spangenberg1 , 2
  • 1E. Scheurich Pharmwerk GmbH, D-7604 Appenweier, Federal Republic of Germany
  • 2Dr. Bernd Spangenberg, Am Rittweg 10, D-7600 Offenburg, Federal Republic of Germany
Further Information

Publication History

1990

Publication Date:
05 January 2007 (online)

Abstract

In garlic (Allium sativum L.) the enzyme alliin lyase catalyzes the cleavage of alliin into allicin which reacts further to furnish ajoene. A simultaneous determination of allicin and ajoene is introduced which, in contrast to the determination of alliin only, allows for the testing of the activity of alliin lyase. It can be demonstrated that at a pH value of less than 3 the enzyme produces only small amounts of allicin. For this reason preparations from garlic should be administered only as enteric-coated formulations.

    >