Production of Sanguinarine by Chelidonium majus Callus Cultures

M. L. Colombo; F. Tomé

doi:10.1055/s-2006-960141

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Planta Med 1991; 57(5): 428-429
DOI: 10.1055/s-2006-960141

Papers

Production of Sanguinarine by Chelidonium majus Callus Cultures

M. L. Colombo¹ , F. Tomé²

¹Istituto di Scienze Farmacologiche, Università di Milano, Via Balzaretti 9, I-20133 Milano, Italy
²Dipartimento di Biologia, Università di Milano, Via Celoria 26, I-20133 Milano, Italy

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Publication History

1990

Publication Date:
05 January 2007 (online)

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Abstract

Tissue callus cultures originating from Chelidonium majus L. seeds were established on Gamborg B5, Murashige-Skoog (MS), and Schenk-Hildebrandt (SH) media. In all experimental conditions, calli accumulated a complex pattern of isoquinoline derivatives. The highest values, both in growth and in sanguinarine production, were obtained using SH medium.

Key words

Chelidonium majus L. - Papaveraceae - callus cultures - B5 medium - MS medium - SH medium - isoquinoline alkaloids