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Planta Med 1991; 57(5): 440-443
DOI: 10.1055/s-2006-960145
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© Georg Thieme Verlag Stuttgart · New York

Bicascarosides in Fluid Extracts of Cascara1

P. de Witte, J. Cuveele, J. Lemli
  • Laboratory of Pharmaceutical Biology and Phytopharmacology, Institute of Pharmaceutical Sciences, K. U. Leuven, Van Evenstraat 4, B-3000 Leuven, Belgium
1 Studies in the Field of Drugs containing Anthracene Derivatives: XXXVII. For Part XXXVI, see Ref. (2)
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1990

Publikationsdatum:
05. Januar 2007 (online)

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Abstract

Bianthraquinone glycosides are formed during the preparation and conservation of fluid extracts of cascara. Analysis of these preparations has shown that up to 20% of total amount of anthracene glycosides can be dimerized. These dimers are devoid of laxative activity. They are absorbed in the intestine and very slowly excreted.

Key words

Anthracene derivatives - cascara extracts - bianthraquinones - bicascarosides - bialoins - pharmacological properties