DNA Binding Alkaloids from Prosopis alba

Astudillo S. Luis; Jürgens S. Karin; Guillermo Schmeda-Hirschmann; Gerald A. Griffith; David J. Holt; Paul R. Jenkins

doi:10.1055/s-2006-960454

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Planta Med 1999; 65(2): 161-162
DOI: 10.1055/s-2006-960454

Letters

DNA Binding Alkaloids from Prosopis alba

Astudillo S. Luis¹ , Jürgens S. Karin¹ , Guillermo Schmeda-Hirschmann¹ , Gerald A. Griffith² , David J. Holt² , Paul R. Jenkins²

¹Institute de Química de Recursos Naturales, Universidad de Talca, Talca, Chile
²Department of Chemistry, Leicester University, Leicester, England

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1998

1998

Publication Date:
04 January 2007 (online)

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Abstract

The known β-phenethylamine (1) and the new alkaloid 2-β-methyl-3-β-hydroxy-6-β-piperidinedodecanol (2) were isolated from the aerial parts of Prosopis alba. Both compounds showed DNA binding effects of 27 and 50%, respectively, at 0.50 mg/ml.