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Planta Med 1990; 56(1): 63-65
DOI: 10.1055/s-2006-960885
Paper

© Georg Thieme Verlag Stuttgart · New York

In Vitro Antimalarial Activity of Coutarea latiflora and Exostema caribaeum Extracts on Plasmodium falciparum

S. Noster1 , 2 , Lj. Kraus1
  • 1Lehrstuhl für Pharmakognosie der Universität Hamburg, Bundesstraße 43, D-2000 Hamburg 13, Federal Republic of Germany
  • 2Part of the planned Ph.D. thesis of S. N. (scholar of “Stiftung zur Förderung der Erfahrungsheilkunde im Stifterverband für die Deutsche Wissenschaft”)
Further Information

Publication History

1989

Publication Date:
05 January 2007 (online)

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Abstract

The medicinal plants, Coutarea latiflora Sesse & Moc. ex. DC. (Hintonia latiflora Bullock) (Rubiaceae) and Exostema caribaeum (Jacq.) Roem. et Schult. (Rubiaceae) were examined for antimalarial properties. Among different crude solvent extracts of the stem bark, the hydrolysed ethyl acetate extracts were shown to have the most potent in vitro antimalarial activity. One compound isolated from the ether extract from Exostema caribaeum showed only moderate activity.

Key words

Coutarea latiflora - Exostema caribaeum - Rubiaceae - in vitro antimalarial activity - 4-phenylcoumarin