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Planta Med 1990; 56(1): 70-72
DOI: 10.1055/s-2006-960887
Paper

© Georg Thieme Verlag Stuttgart · New York

Cytostatic and Antibacterial Activity of Some Compounds Isolated from Several Lamiaceae Species from the Canary Islands

V. Darias, L. Bravo, R. Rabanal, C. C. Sánchez-Mateo, D. A. Martín-Herrera
  • Departamento de Farmacognosia y Farmacodinamia, Facultad de Farmacia, Universidad de La Laguna, Tenerife, Canary Islands, Spain
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Publication History

1988

Publication Date:
05 January 2007 (online)

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Abstract

A chemotherapeutic study has been carried out on thirteen products Eeleven diterpenes, one lignan, (+)-sesamin, and a coumarin, siderin] isolated from Salvia and Sideritis species considered endemic to the Canarian flora. The data obtained suggest that some diterpenoid compounds show an interesting cytostatic activity, specially galdosol (6) with an ID50 value of 0.5 µg/ml. These compounds also evidence a moderate antibacterial activity against Gram positive bacteria.

Key words

Salvia - Sideritis - Lamiaceae - cytostatic activity - antibacterial activity