Triterpenoid Saponins from Anemone flaccida

Abstract

From the rhizome of Anemone flaccida Fr. Schmidt, used in Chinese folk medicine, four saponins of oleanolic acid-A,B,C,D were isolated. By means of spectroscopy and chemical transformation, saponins A, B, and D were identified as 3-O-[α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyrasyl]-oleanolic acid, 3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl]-oleanolic acid, and 3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl]-oleanolic acid. These three saponins are known compounds but isolated from Anemone plants for the first time. Saponin C was elucidated as 3-O-[β-D-glucopyranosyl-(1→2)-β-D-xylopyranosy1]-oleanolic acid, which has not been reported in the literature before, and is named as flaccidoside I.

Key words

Anemone flaccida - saponin - flaccidoside I