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Planta Med 1992; 58(1): 22-25
DOI: 10.1055/s-2006-961382
Paper

© Georg Thieme Verlag Stuttgart · New York

An Evaluation of Lawsonia alba Extract as Hepatoprotective Agent

K. K. Anand, B. Singh, D. Chand, B. K. Chandan
  • Department of Pharmacology, Regional Research Laboratory, Canal Road, Jammu Twai 180001 India
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Publication History

1991

Publication Date:
04 January 2007 (online)

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Abstract

The hepatoprotective activity of an ethanol-water (1:1) extract of Lawsonia alba has been studied against CCl4-induced liver toxicity. The effects of the extract on hexobarbitone-induced sleep, BSP clearance, and on certain biochemical parameters indicated its protective role. There was no effect on bile flow. The extract did not show any signs of toxicity and the minimum lethal dose was greater than 2.0 g/kg p.o. in mice.

Key words

Lawsonia alba - hepatoprotective activity - CCl4-induced liver toxicity - hexobarbitone-induced sleep - BSP clearance