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Planta Med 1992; 58(5): 405-409
DOI: 10.1055/s-2006-961501
Paper

© Georg Thieme Verlag Stuttgart · New York

Effects of Phaeodactylum tricornutum and Dunaliella tertiolecta Extracts on the Central Nervous System

R. Villar, M. R. Laguna, J. M. Calleja, I. Cadavid
  • Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Farmaria, Universidad de Santiago de Compostela, Galicia, Spain
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Publication History

1991

Publication Date:
05 January 2007 (online)

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Abstract

Continuing work on the effects of aqueous extracts of the microalgae Phaeodactylum tricornutum Bohlin (Bacillariophyceae) and Dunaliella tertiolecta Butcher (Chlorophyceae) on the central nervous system, we report their effects on spontaneous motor activity, rectal temperature, exploratory behaviour, muscle relaxation, catalepsy, and conditioned avoidance responses. Both extracts showed activity as a CNS depressant and a potential muscle relaxant, the latter more marked in the case of P. tricornutum.

Key words

Phaeodactylum tricornutum - Dunaliella tertiolecta - CNS activity - muscle relaxant activity