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Planta Med 1992; 58(6): 496-498
DOI: 10.1055/s-2006-961534
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© Georg Thieme Verlag Stuttgart · New York

Analgesic and Anti-Inflammatory Effects of Ranunculus japonicus Extract

Bo-Jin Cao, Qing-Yu Meng, Nan Ji
  • Department of Pharmacology, Hunan Institute of Pharmaceutical Industry, Changsha 410014, People's Republic of China
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Publication History

1991

Publication Date:
05 January 2007 (online)

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Abstract

The analgesic and anti-inflammatory effects of Ranunculus japonicus extract after parenteral administration were determined in several animal models. The extract inhibited the mice writhing responses caused by acetic acid and raised the pain thresholds of mice in the hot-plate test. The extract also inhibited the paw edema of rats induced by carrageenin, ear swelling of mice caused by xylene, mice vascular permeability increase induced by acetic acid, and granuloma formation in rats.

Key words

Ranunculus japonicus - analgesic activity - anti-inflammatory activity - pharmacology