New Hepatoprotective Triterpenes form Canarium album

Masaharu Tamai; Naoharu Watanabe; Mayumi Someya; Hideaki Kondoh; Sadafumi Omura; Zhang Pei Ling; Rao Chang; Chen Wei Ming

doi:10.1055/s-2006-961822

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Planta Med 1989; 55(1): 44-47
DOI: 10.1055/s-2006-961822

Papers

New Hepatoprotective Triterpenes form Canarium album

Masaharu Tamai¹ , Naoharu Watanabe¹ , Mayumi Someya¹ , Hideaki Kondoh¹ , Sadafumi Omura¹ , Zhang Pei Ling² , Rao Chang² , Chen Wei Ming²

¹Research Center, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Ohmiya, Saitama 330, Japan
²Institute of Materia Medica, Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing, Peoples' Republic of China

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Publication History

1987

Publication Date:
24 January 2007 (online)

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Abstract

Canarium album has yielded seven triterpenes of which two appear to be novel. The new triterpenes, which were identified on the basis of spectral characteristics, are urs-12-ene-3α, 16β-diol and olean-2-ene-3α, 16β-diol. Both compounds exhibited hepatoprotective activity in primary cultured rat hepatocytes intoxicated with D-galactosamine.