Investigation of the Anti-Snake Venom Activity of Schumanniophyton magnificum

P. J. Houghton; A. L. Harvey

doi:10.1055/s-2006-962002

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Planta Med 1989; 55(3): 273-275
DOI: 10.1055/s-2006-962002

Papers

Investigation of the Anti-Snake Venom Activity of Schumanniophyton magnificum

P. J. Houghton¹ , A. L. Harvey²

¹Pharmacognosy Research Laboratories, Chelsea Department of Pharmacy, King's College London (KQC), Manresa Rd, London SW3 6LX, U.K.
²Department of Physiology and Pharmacology, University of Strathclycde, 204 George St, Glasgow G1 1XW, U.K.

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Publication History

1988

Publication Date:
24 January 2007 (online)

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Abstract

Polar fractions of the methanolic extracts of the stem- and root-barks of Schumanniophyton magnificum (Rubiaceae) reduced the effects of cobra venom cardiotoxin in the chick biventer cervicis nerve-muscle preparation in vitro. No activity was observed against a curaremimetic neurotoxin from cobra venom. Further fractionation of the extracts showed that the activity was not due to alkaloidal components, but the active substances could not be identified or isolated.