Alkaloids from Rauwolfia cubana Stem Bark

Jorge A. Martinez; Carlos Gomez; Tamara Santana; Herman Velez

doi:10.1055/s-2006-962005

Planta Medica, Table of Contents

Planta Med 1989; 55(3): 283-285
DOI: 10.1055/s-2006-962005

Papers

Alkaloids from Rauwolfia cubana Stem Bark

Jorge. A. Martinez¹ , Carlos Gomez¹ , Tamara Santana¹ , Herman Velez²

¹Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Havana, San Làzaro y L, Ciudad de la Havana 4, Cuba
²National Center of Scientific Research, Apto. Postal 6990, Ave. 25 y calle 158, Cubanacan, Playa, Ciudad de la Havana, Cuba

Abstract

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Abstract

Six indole alkaloids, tetrahydroalstonine, aricine, 16-epi-affinine, ajmaline, amerovolfine, and amerovolficine have been isolated from the ethanolic extract of the stem bark of Rauwolfia cubana A. DC. Amerovolfine (N ^α-demethylaccedine) and amerovolficine (16-demethoxy-carbonylpagicerine) are new alkaloids related to 16-epi-affinine, and their structures have been determined by spectroscopic analysis.

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