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DOI: 10.1055/s-2006-962024
© Georg Thieme Verlag Stuttgart · New York
An Ethnopharmacognostic Approach to the Search for Immunomodulators of Plant Origin
Publication History
1988
Publication Date:
24 January 2007 (online)
Abstract
The search for immunomodulating plant constituents through basic and field inquiries into the literature and practices of traditional Indian medicine is treated. The strategy of data collecting proceeds through aspects of an ethnobotanical, an ethnopharmaceutical, an ethnopharmacological, and an ethnomedical nature. In the experimental immunopharmacognostic phase, immunomodulatory compounds are isolated and purified through action-guided fractionation procedures. The results described here refer to activities found on human complement activation and on PMN leucocytes activation. The immunomodulating plant compounds included in this report were isolated from Azadirachta indica bark, Woodfordia fructicosa flowers, Picrorhiza kurroa roots, and Jatropha multifida latex.
3 Plenary Lecture at the 36th Annual Congress of the Society for Medicinal Plant Research, Freiburg, 12. to 16.9.1988