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Planta Med 1988; 54(1): 24-27
DOI: 10.1055/s-2006-962323
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© Georg Thieme Verlag Stuttgart · New York

Chemistry of Acronycine; Part 1. Synthesis of 1-Hydroxy-1,2-dihydroacronycine and 2-Hydroxy-1,2-dihydroacronycine

Sofia Mitaku, Alexios-Léandros Skaltsounis, François Tillequin, Michel Koch
  • Départment de Pharmacognosie de l'Université René Descartes, UA au CNRS No. 484, Faculté des Sciences Pharmaceutiques et Biologiques, 4, avenue de l'Observatoire, F-75006 Paris, France.
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Publication History

1987

Publication Date:
24 January 2007 (online)

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Abstract

The synthesis of the potential acronycine prodrugs, 1-hydroxy-1,2-dihydroacronycine (2) and 2-hydroxy-1,2-dihydroacronycine (3) are described using the natural alkaloid acronycine (1) as starting material.