Simultaneous Determination of Six Alkaloids in Ephedrae Herba by High Performance Liquid Chromatography

Zhang Jian; Tian Zhen; Lou Zhi-cen

doi:10.1055/s-2006-962342

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Planta Med 1988; 54(1): 69-70
DOI: 10.1055/s-2006-962342

Papers

Simultaneous Determination of Six Alkaloids in Ephedrae Herba by High Performance Liquid Chromatography

Zhang Jian, Tian Zhen, Lou Zhi-cen

Department of Pharmacognosy, School of Pharmacy, Beijing Medical University, Beijing 100083, Peoples' Republic of China.

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Publication History

1987

Publication Date:
24 January 2007 (online)

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Abstract

A new and rapid analytical method for the simultaneous determination of six Ephedra alkaloids (ephedrine, pseudoephedrine, norephedrine, norpseudoephedrine, methylephedrine, and methylpseudoephedrine) in Ephedrae Herba by high performance liquid chromatography (HPLC) has been developed. Recoveries of each alkaloid were 96.0-101.6% with coefficients of deviation of 1.7-3.0%. The contents of six alkaloids in three species of Ephedra indigenous to China are determined and reported.